Sarah Gore, 28, married Bill Lee, 36, a Los Angeles businessman, said spokeswoman Kalee Kreider.
Kreider declined to give any further details.
The daughter of the former vice president and Democratic presidential nominee is a Harvard graduate and a medical student at the University of California, San Francisco.
Sarah is the thirdoldest child of Al and Tipper Gore. Their oldest daughter, Karenna, 34, is married to Drew Schiff. Kristin Gore, 30, is married to Paul Cusack. Al Gore III, 24, is single and lives in Los Angeles.